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Circulation of Influenza A(H5N8) Virus, Saudi Arabia

Hussain Al-Ghadeer et al. Emerg Infect Dis. 2018 Oct.

Abstract

Highly pathogenic avian influenza A(H5N8) viruses have been detected in several continents. However, limited viral sequence data are available from countries in the Middle East. We report full-genome analyses of highly pathogenic H5N8 viruses recently detected in different provinces in Saudi Arabia.

Keywords: Saudi Arabia; influenza; influenza A(H5N8); outbreak; phylogenetic analysis; viruses.

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Figures

Figure
Figure
Phylogenetic analysis of hemagglutinin sequences of influenza A(H5N8) viruses detected in oropharyngeal and cloacal swab samples from birds in Saudi Arabia. Aligned sequences were analyzed in MEGA7 (http://www.megasoftware.net). We constructed the phylogenetic tree using the neighbor-joining method. Representative viral sequences and viral sequences that are highly similar to those reported in this study were included in the analysis. H5N8 viruses reported in this study are labeled. Bootstrap values ≥60% are shown. Representative viruses sharing a similar gene constellation as the H5N8 viruses found in Saudi Arabia are underlined (see text for details). Virus isolate numbers (EPI ISL) in GISAID (http://platform.gisaid.org) or gene accession numbers in GenBank for corresponding viral sequences are provided. Scale bar indicates estimated genetic distance.
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