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Case Reports
. 2018 Jun 20:5:e47.
doi: 10.14309/crj.2018.47. eCollection 2018.

Development of Drug-Induced Inverse Psoriasis in a Patient with Crohn's Disease

Evan Darwin  1 , Amar Deshpande  2 , Hadar Lev-Tov  1
Affiliations
Case Reports

Development of Drug-Induced Inverse Psoriasis in a Patient with Crohn's Disease

Evan Darwin et al. ACG Case Rep J. .

Abstract

Crohn's disease is difficult to manage and often requires multiple medications. While these drugs vastly improve quality of life, physicians must monitor for adverse events. We report a case of a flare of inverse psoriasis after 15 months of treatment with ustekinumab. This is the third reported case of a flare of drug-induced psoriasis with ustekinumab, and it is the first reported case with an inverse presentation; however, the clinical picture is confounded by concomitant use of hydroxychloroquine. Inverse psoriasis is a rare variant of drug-induced psoriasis of which physicians must be cognizant while treating patients with Crohn's disease.

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Figures

Figure 1
Figure 1
Psoriasiform rash at presentation.
Figure 2
Figure 2
Psoriasiform rash after 2 months of treatment with topical tacrolimus and pulse clobetasol cream.
See this image and copyright information in PMC

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