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Comment
. 2018 Jun 28;44(1):73.
doi: 10.1186/s13052-018-0515-8.

Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk

Alberto Berardi  1   2 , Chryssoula Tzialla  3 , Laura Travan  4 , Jenny Bua  4 , Daniele Santori  5 , Milena Azzalli  6 , Caterina Spada  7 , Laura Lucaccioni  8 ; GBS Prevention Working Group of Emilia-Romagna
Collaborators, Affiliations
Comment

Secondary prevention of early-onset sepsis: a less invasive Italian approach for managing neonates at risk

Alberto Berardi et al. Ital J Pediatr. .

Abstract

Strategies to prevent early-onset sepsis (EOS) have led to a substantial decline in many countries. However, one of the most controversial topics in neonatology is the management of asymptomatic full-term and late preterm neonates at risk for EOS, and guidelines lack substantial consensus regarding this issue. A strategy for managing neonates, entirely based on serial physical examinations, has been developed in two Italian regions. This strategy seems safe, while reducing laboratory tests and unnecessary antibiotics. In the current commentary we provide area-based data concerning the prevention of EOS in 2 northern Italian regions, and we detail the results of their strategy for managing healthy-appearing newborns at risk for EOS.

Keywords: Group B streptococcus; Intrapartum antibiotic prophylaxis; Neonatal sepsis; Newborn infant; Prevention; Risk factors.

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Conflict of interest statement

Ethics approval and consent to participate

Not applicable.

Consent for publication

Not applicable.

Competing interests

The authors declare that they have no competing interests.

Dr. Alberto Berardi has received funding from the Agenzia Sanitaria Regione dell’Emilia-Romagna: “Assegnazione e concessione di finanziamenti alle Aziende Sanitarie Regionali per la realizzazione di programmi di interesse regionale a sostegno del Piano Regionale della Prevenzione 2015-2018 C.U.P. n. E43G17000680002”.

The remaining authors declare they have no funding source.

Financial disclosure: Dr. Alberto Berardi has received fees from these Companies: Pfizer.

(2015), Putnam Associates (2016) and GSK (2017).

Publisher’s Note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Comment on

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