Lean on Me: Cell-Cell Interactions Release TGF-β for Local Consumption Only
- PMID: 29958107
- DOI: 10.1016/j.cell.2018.06.008
Lean on Me: Cell-Cell Interactions Release TGF-β for Local Consumption Only
Abstract
A new study combines detailed biochemical characterization with whole-animal genetics and computational transcriptome data mining to reveal how the LRRC33 milieu molecule imposes an exquisite level of spatial control on TGF-β signaling in the CNS.
Copyright © 2018 Elsevier Inc. All rights reserved.
Comment on
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A Milieu Molecule for TGF-β Required for Microglia Function in the Nervous System.Cell. 2018 Jun 28;174(1):156-171.e16. doi: 10.1016/j.cell.2018.05.027. Epub 2018 Jun 14. Cell. 2018. PMID: 29909984 Free PMC article.
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