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Case Reports
. 2018 Nov;7(2):313-315.
doi: 10.1007/s13730-018-0349-7. Epub 2018 Jun 29.

Paraplegia as a presentation of primary hyperoxaluria

Yannick Dieudonné  1 , Laure Eprinchard  1 , Emilie Léon  1 , Pierre Oswald  2 , Anne Gressel  3 , Sophie Carre  4 , Yves Dimitrov  5
Affiliations
Case Reports

Paraplegia as a presentation of primary hyperoxaluria

Yannick Dieudonné et al. CEN Case Rep. 2018 Nov.

Abstract

30% of the patients suffering from hyperoxaluria type 1 are diagnosed only when they already had reached end-stage renal disease. We report the case of a 57-year-old woman with history of chronic kidney failure presenting with paraplegia due to spinal cord compression by thoracic mass-like lesions. Bone biopsy specimen obtained by decompressive laminectomy revealed calcium oxalate deposits. Once diagnosis of primary hyperoxaluria was confirmed, she underwent haemodialysis with incomplete improvement of her neurological disorders and was registered on the waiting list for transplantation.

Keywords: End-stage renal disease; Hyperoxaluria; Nephrocalcinosis; Oxalosis; Paraplegia.

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Conflict of interest statement

Conflict of interest

The authors have declared that no conflict of interest exists.

Ethical approval

This article does not contain any studies with human participants or animals performed by any of the authors.

Informed consent

Written informed consent was obtained from the patient’s parents for publication of this case report and accompanying images. A copy of the written consent may be requested for review from the corresponding author.

Figures

Fig. 1
Fig. 1
Spinal MRI (T2 sequency) thoracic mass-like lesion with spinal cord compression (T2–T3 level, arrow)
See this image and copyright information in PMC

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