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. 2019 Sep-Oct;95(5):538-544.
doi: 10.1016/j.jped.2018.05.010. Epub 2018 Jun 28.

ERICA: smoking is associated with more severe asthma in Brazilian adolescents

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Free article

ERICA: smoking is associated with more severe asthma in Brazilian adolescents

Erica Azevedo de Oliveira Costa Jordão et al. J Pediatr (Rio J). 2019 Sep-Oct.
Free article

Abstract

Objective: To investigate the association between smoking and asthma, and possible associated factors in Brazilian adolescents.

Methods: A cross-sectional, national, school-based study with adolescents aged 12-17 years, participants in the Study of Cardiovascular Risks in Adolescents (Estudo de Riscos Cardiovasculares em Adolescentes - ERICA). A total of 66,394 participants answered a self-administered questionnaire with questions about asthma, smoking, lifestyle and sociodemographic variables. Bivariate analysis between Current Asthma (CA) and Severe Asthma (SA) and the other study variables were performed using Chi-squared. Then, the crude and adjusted Prevalence Ratios (PR), and respective 95% Confidence Intervals (95% CI) of current asthma/severe asthma and smoking variables, corrected for sociodemographic and lifestyle variables, were estimated using generalized linear models with Poisson regression, logit link, and robust variance.

Results: The prevalence of current asthma and severe asthma were significantly higher in adolescents who were exposed to: experimentation (current asthma: PR=1.78, 95% CI: 1.51-2.09; severe asthma: PR=2.01; 95% CI: 1.35-2.98); current smoking (current asthma: PR=2.08, 95% CI: 1.65-2.64; severe asthma: PR=2.29; 95% CI: 1.38-3.82); regular smoking (current asthma: PR=2.25, 95% CI: 1.64-3.07; severe asthma: PR: 2.41; 95% CI: 1.23-4.73); and passive smoking (current asthma: PR=1.47, 95% CI: 1.27-1.67; severe asthma: PR=1.66; 95% CI: 1.19-2.32); these associations remained significant after adjustment.

Conclusions: Asthma and smoking were significantly associated in Brazilian adolescents, regardless of the sociodemographic and lifestyle factors, notably in those with more severe disease.

Keywords: Adolescent; Adolescente; Asma; Asthma; Epidemiological studies; Estudo epidemiológico; Smoking; Tabagismo.

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