Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Jun 27;42(3):406-415.
doi: 10.5535/arm.2018.42.3.406.

Efficacy and Safety of Caregiver-Mediated Exercise in Post-stroke Rehabilitation

Min Jun Lee  1 , Seihee Yoon  1 , Jung Joong Kang  1 , Jungin Kim  1 , Jong Moon Kim  1 , Jun Young Han  1
Affiliations

Efficacy and Safety of Caregiver-Mediated Exercise in Post-stroke Rehabilitation

Min Jun Lee et al. Ann Rehabil Med. .

Abstract

Objective: To assess the efficacy and safety of our 4-week caregiver-mediated exercise (CME) in improving trunk control capacity, gait, and balance and in decreasing concerns about post-stroke falls when there is an increase in its efficacy.

Methods: Acute or subacute stroke survivors were assigned to either the trial group (n=35) or the control group (n=37). Changes in Modified Barthel Index (MBI), Functional Ambulation Categories (FAC), Berg Balance Scale (BBS), and Trunk Impairment Scale (TIS) scores at 4 weeks from baseline served as primary outcome measures. Correlations of primary outcome measures with changes in Fall Efficacy Scale-International (FES-I) scores at 4 weeks from baseline in the trial group served as secondary outcome measures. Treatment-emergent adverse events (TEAEs) served as safety outcome measures.

Results: There were significant differences in changes in MBI, FAC, BBS, TIS-T, TIS-D, TIS-C, and FES-I scores at 4 weeks from baseline between the two groups (all p<0.0001). There were no significant (p=0.0755) differences in changes in TIS-S scores at 4 weeks from baseline between the two groups. MBI, FAC, BBS, and TIS scores showed significantly inverse correlations with FES-I scores in patients receiving CME. There were no TEAEs in our series.

Conclusion: CME was effective and safe in improving the degree of independence, ambulation status, dynamic and static balance, trunk function, and concerns about post-stroke falls in stroke survivors.

Keywords: Caregivers; Exercise; Gait; Postural balance; Stroke.

PubMed Disclaimer

Figures

Fig. 1.
Fig. 1.
Study schema.
Fig. 2.
Fig. 2.
Study flow chart.
Fig. 3.
Fig. 3.
Correlations of MBI, BBS, FAC, and TIS scores with FES-I scores. Linear relation (A) between MBI and FES-I scores, (B) between BBS and FES-I scores, (C) between FAC and FES-I scores, and (D) between TIS and FES-I scores. MBI, Modified Barthel Index; BBS, Berg Balance Scale; FAC, Functional Ambulation Category; TIS, Trunk Impairment Scale; FES-I, Fall Efficacy Scale-International.
See this image and copyright information in PMC

References

    1. Vloothuis J, Mulder M, Nijland RH, Konijnenbelt M, Mulder H, Hertogh CM, et al. Caregiver-mediated exercises with e-health support for early supported discharge after stroke (CARE4STROKE): study protocol for a randomized controlled trial. BMC Neurol. 2015;15:193. - PMC - PubMed
    1. Belgen B, Beninato M, Sullivan PE, Narielwalla K. The association of balance capacity and falls self-efficacy with history of falling in community-dwelling people with chronic stroke. Arch Phys Med Rehabil. 2006;87:554–61. - PubMed
    1. Zijlstra GA, van Haastregt JC, van Rossum E, van Eijk JT, Yardley L, Kempen GI. Interventions to reduce fear of falling in community-living older people: a systematic review. J Am Geriatr Soc. 2007;55:603–15. - PubMed
    1. Pajala S, Era P, Koskenvuo M, Kaprio J, Tormakangas T, Rantanen T. Force platform balance measures as predictors of indoor and outdoor falls in communitydwelling women aged 63-76 years. J Gerontol A Biol Sci Med Sci. 2008;63:171–8. - PubMed
    1. Kosse NM, de Groot MH, Vuillerme N, Hortobagyi T, Lamoth CJ. Factors related to the high fall rate in longterm care residents with dementia. Int Psychogeriatr. 2015;27:803–14. - PubMed

LinkOut - more resources