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Review
. 2018;59(2):127-132.
doi: 10.2209/tdcpublication.2017-0028.

Congenital Epulis: A Case and Review of the Literature

Katsutoshi Kokubun  1 , Kenichi Matsuzaka  1 , Yoshihiko Akashi  1 , Masami Sumi  1 , Kei Nakajima  1 , Satoshi Murakami  1 , Masato Narita  2 , Takahiko Shibahara  2 , Takashi Inoue  1
Affiliations
Free article
Review

Congenital Epulis: A Case and Review of the Literature

Katsutoshi Kokubun et al. Bull Tokyo Dent Coll. 2018.
Free article

Abstract

Congenital epulis is an unusual benign oral mucosal lesion in newborns with no tendency to recur after excision. The histogenesis of the lesion is unknown, but it is believed to be of mesenchymal origin. We describe a case of congenital epulis (20×10 mm) in the mandibular gingiva of a newborn. The mass, which was smooth-surfaced and pedunculated with a healthy color, was surgically removed at 5 months post-birth. Histologically, the tumor consisted mainly of large eosinophilic granular cells. Immunohistochemical studies revealed intense staining for vimentin, STRO-1, and CD44, suggesting that it was derived from mesenchymal cells. The literature and immunohistochemical profile of congenital epulis are also discussed.

Keywords: Congenital epulis; Granular cell; Immunohistochemistry; Mesenchymal cell; Origin.

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