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. 1985;6(2):131-6.
doi: 10.1007/BF02235744.

Cellular retinol-binding protein in normal and neoplastic human mammary gland

Cellular retinol-binding protein in normal and neoplastic human mammary gland

G Fex et al. Breast Cancer Res Treat. 1985.

Abstract

The concentration of cellular retinol-binding protein (CRBP) was determined in samples of normal and neoplastic mammary gland, using a specific and sensitive radioimmunoassay. The CRBP concentration was significantly higher in neoplastic tissue, but detectable levels were also present in all samples of normal gland. Tubulo-ductal cancers had significantly lower CRBP levels than other cancer types. The CRBP concentration of the neoplastic tissue showed no correlation with the concentration of progesterone or estrogen receptor.

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