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. 1985 Oct 12;291(6501):997-8.
doi: 10.1136/bmj.291.6501.997.

Variation in human T lymphotropic virus III (HTLV-III) antibodies in homosexual men: decline before onset of illness related to acquired immune deficiency syndrome (AIDS)

R J Biggar, M Melbye, P Ebbesen, S Alexander, J O Nielsen, P Sarin, V Faber

Variation in human T lymphotropic virus III (HTLV-III) antibodies in homosexual men: decline before onset of illness related to acquired immune deficiency syndrome (AIDS)

R J Biggar et al. Br Med J (Clin Res Ed). .

Abstract

Western blot analysis was used to document the development and changes in human T lymphotropic virus III (HTLV-III) antibody among Danish homosexual men followed longitudinally over three years. Reactivity against p15, p24, and p55 appeared earliest. After seroconversion the antibody concentration fluctuated, but in one instance a steady decline in banding intensity was seen during the 18 months before onset of the acquired immune deficiency syndrome (AIDS) and throughout the remaining eight months of his life.

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References

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