Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 Sep;32(9):2058-2062.
doi: 10.1038/s41375-018-0191-0. Epub 2018 Jul 2.

Whole-exome sequencing exploration of acquired uniparental disomies in B-cell precursor acute lymphoblastic leukemia

Kristina B Lundin-Ström  1 , Andrea Biloglav  2 , Henrik Lilljebjörn  2 , Marianne Rissler  2 , Thoas Fioretos  2   3 , Markus Hansson  4 , Mikael Behrendtz  5 , Anders Castor  6 , Linda Olsson  3 , Bertil Johansson  2   3
Affiliations

Whole-exome sequencing exploration of acquired uniparental disomies in B-cell precursor acute lymphoblastic leukemia

Kristina B Lundin-Ström et al. Leukemia. 2018 Sep.
No abstract available

PubMed Disclaimer

Conflict of interest statement

Compliance with ethical standards

The investigation was approved by the Research Ethics Committee of Lund University and informed consent for the analyses was obtained according to the Declaration of Helsinki.

Conflict of interest

The authors declare that they have no conflict of interest.

Figures

Fig. 1
Fig. 1
Flowchart of the number of cases and wUPDs/sUPDs investigated in the various analysis steps
See this image and copyright information in PMC

References

    1. Raghavan M, Lillington DM, Skoulakis S, Debernardi S, Chaplin T, Foot NJ, et al. Genome-wide single nucleotide polymorphism analysis reveals frequent partial uniparental disomy due to somatic recombination in acute myeloid leukemias. Cancer Res. 2005;65:375–8. - PubMed
    1. Score J, Cross NCP. Acquired uniparental disomy in myeloproliferative neoplasms. Hematol Oncol Clin North Am. 2012;26:981–91. doi: 10.1016/j.hoc.2012.07.002. - DOI - PubMed
    1. Fitzgibbon J, Smith LL, Raghavan M, Smith ML, Debernardi S, Skoulakis S, et al. Association between acquired uniparental disomy and homozygous gene mutation in acute myeloid leukemias. Cancer Res. 2005;65:9152–4. doi: 10.1158/0008-5472.CAN-05-2017. - DOI - PubMed
    1. Lundin KB, Olsson L, Safavi S, Biloglav A, Paulsson K, Johansson B. Patterns and frequencies of acquired and constitutional uniparental isodisomies in pediatric and adult B-cell precursor acute lymphoblastic leukemia. Genes Chromosomes Cancer. 2016;55:472–9. doi: 10.1002/gcc.22349. - DOI - PubMed
    1. Gupta M, Raghavan M, Gale RE, Chelala C, Allen C, Molloy G, et al. Novel regions of acquired uniparental disomy discovered in acute myeloid leukemia. Genes Chromosomes Cancer. 2008;47:729–39. doi: 10.1002/gcc.20573. - DOI - PubMed

Publication types

MeSH terms

LinkOut - more resources