A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes
- PMID: 2996845
- DOI: 10.1007/BF00327469
A cloned sequence, p82H, of the alphoid repeated DNA family found at the centromeres of all human chromosomes
Abstract
Clone p82H is a human DNA sequence which hybridises in situ exclusively to the centromeric regions of all human chromosomes. It is composed of approximately 14 tandemly repeated variants of a basic 172 bp sequence, and is related to the alphoid family. The organisation of the family of cross-hybridising sequences, detected by the clone p82H, is described both in the human genome and on certain chromosomes, and its relationship to known sequence families is discussed.
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