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. 2018 Jul 3;11(1):431.
doi: 10.1186/s13104-018-3524-1.

Efficacy of a Salmonella live vaccine for turkeys in different age groups and antibody response of vaccinated and non-vaccinated turkeys

Martina Hesse  1 , Andreas Stamm  2 , Rita Weber  2 , Gerhard Glünder  2
Affiliations

Efficacy of a Salmonella live vaccine for turkeys in different age groups and antibody response of vaccinated and non-vaccinated turkeys

Martina Hesse et al. BMC Res Notes. .

Abstract

Objective: Human Salmonellosis continues to be one of the most important foodborne zoonoses worldwide, although a decrease in case numbers has been noted in recent years. It is a foodborne zoonotic infection most commonly associated with the consumption of raw egg products but also with meat consumption including the consumption of poultry products. Turkey flocks in Europe have been reported to be affected by Salmonella infection, too. The present study examines the efficacy of a newly licensed Salmonella life vaccine in reducing infections with the Salmonella serovars Typhimurium and Enteritidis in turkeys. Turkeys were vaccinated the first day of life and at the age of 6 and 16 weeks. Groups of birds which had received different numbers of vaccinations were then submitted to challenge trials with either SE or ST.

Results: In vaccinated birds Salmonella counts in liver and spleen and, less effectively, in caecum were reduced compared to unvaccinated birds. In several groups serum antibody-titers were statistically significantly higher in vaccinated turkeys than in non-vaccinated ones at day seven post infection, but only in one out of six groups at day 14 post infection.

Keywords: Antibody response; Immunization; Salmonella; Turkey.

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Figures

Fig. 1
Fig. 1
Re-isolation of virulent Salmonella strains from caecum, liver and spleen in different age groups. Figure bars represent the mean log 10 colony forming units/gram from 10 samples of caecum ingesta, liver or spleen, respectively. Error bars represent standard deviation. Statistically significant differences are indicated by different letters
Fig. 2
Fig. 2
Antibody production after Salmonella infection in different age groups. Figure bars represent the mean log 10 colony forming units/gram from 10 samples of caecum ingesta, liver or spleen, respectively. Error bars represent standard deviation. Statistically significant differences are indicated by different letters
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