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Case Reports
. 2018 Jun 4:2018:8362012.
doi: 10.1155/2018/8362012. eCollection 2018.

Unexpected Liver Embryonal Sarcoma in the Adult: Diagnosis and Treatment

Maurizio Pinamonti  1 , Federico Vittone  2 , Francesco Ghiglione  3 , Andrea Borasi  3 , Stefano Silvestri  4 , Sergio Coverlizza  1
Affiliations
Case Reports

Unexpected Liver Embryonal Sarcoma in the Adult: Diagnosis and Treatment

Maurizio Pinamonti et al. Case Rep Surg. .

Abstract

Undifferentiated embryonal sarcoma of the liver is a malignancy with poor prognosis observed more frequently in children between 6 and 10 years old and very rarely found in adults. We present a case of embryonal sarcoma of the liver in a 60-year-old woman without significant medical history who presented to our attention with constitutional symptoms. Preoperative assessments did not show alterations in blood chemistry or tumor markers. Imaging studies showed a huge mass lying in the right abdominal quadrants, strictly adherent to the liver. The tumor was partially cystic with a thickened wall, sporadic contrast enhancement, and solid component. The patient underwent excision of the mass with associated liver bisegmentectomy S5-S6. Postoperative course was uneventful. The definitive histological diagnosis revealed the presence of embryonal sarcoma of the liver. We describe the clinical, histopathological, and therapeutic options adopted in the multimodal treatment of this disease.

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Figures

Figure 1
Figure 1
(a, b, c) A huge, partially cystic mass with heterogeneous contrast enhancement is seen in the right abdominal quadrant, adjacent to the liver (CT scan).
Figure 2
Figure 2
Mixture of highly atypical spindle and giant cells. The larger cells often contain numerous intracytoplasmic hyaline globules (hematoxylin and eosin, 20x magnification).
Figure 3
Figure 3
Tumor cells show strong membranous expression of CD10 (CD10 immunohistochemistry, 20x magnification).
See this image and copyright information in PMC

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