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. 2018 May-Jun;51(3):352-356.
doi: 10.1590/0037-8682-0241-2017.

Clinical and laboratorial features of oral candidiasis in HIV-positive patients

Regiane Nogueira Spalanzani  1 , Karine Mattos  2 , Luiza Inahe Marques  1 , Pedro Fernando Diniz Barros  2 , Pamela Iruama Peres Pereira  3 , Anamaria Mello Miranda Paniago  2 , Rinaldo Poncio Mendes  4 , Marilene Rodrigues Chang  1   2
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Free article

Clinical and laboratorial features of oral candidiasis in HIV-positive patients

Regiane Nogueira Spalanzani et al. Rev Soc Bras Med Trop. 2018 May-Jun.
Free article

Abstract

Introduction: We describe the clinical and laboratorial features of oral candidiasis in 66 HIV-positive patients.

Methods: Polymerase chain reaction-based techniques were performed for differentiation of Candida spp. isolated from patients at a public teaching hospital in Midwest Brazil.

Results: Oral lesions, mainly pseudomembranous, were significantly related to higher levels of immunosuppression. Of 45 Candida isolates, 66.7% were C. albicans. Most of the isolates were susceptible to the antifungal drugs tested.

Conclusions: Oral lesions were associated with higher immunosuppression levels. Lower susceptibility to antifungals by non-albicans isolates supports the importance of surveillance studies using susceptibility tests to aid in the treatment.

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