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Comment
. 2018 Jul 3;28(1):1-2.
doi: 10.1016/j.cmet.2018.06.015.

Monogenic Obesity; Using Drugs to Bypass the Problem

Anthony P Coll  1
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Monogenic Obesity; Using Drugs to Bypass the Problem

Anthony P Coll. Cell Metab. .
Free article

Abstract

Safe and effective pharmacological treatments for severe obesity remain scarce. In this issue of Cell Metabolism, Iepsen et al. (2018) show that obese patients with pathogenic melanocortin 4 receptor mutations, the most common form of monogenic obesity, lose weight with glucagon-like peptide 1 (GLP-1) receptor agonist therapy.

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