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Review
. 2018 Sep;194(9):797-805.
doi: 10.1007/s00066-018-1329-8. Epub 2018 Jul 4.

Neoadjuvant chemotherapy for breast cancer-background for the indication of locoregional treatment

David Krug  1   2 , René Baumann  3 , Wilfried Budach  4 , Jürgen Dunst  3 , Petra Feyer  5 , Rainer Fietkau  6 , Wulf Haase  7 , Wolfgang Harms  8 , Thomas Hehr  9 , Marc D Piroth  10 , Felix Sedlmayer  11 , Rainer Souchon  12 , Frederik Wenz  13 , Rolf Sauer  6 ; Breast Cancer Expert Panel of the German Society of Radiation Oncology (DEGRO)
Affiliations
Review

Neoadjuvant chemotherapy for breast cancer-background for the indication of locoregional treatment

David Krug et al. Strahlenther Onkol. 2018 Sep.

Abstract

Neoadjuvant chemotherapy (NACT) has been widely adopted into the multidisciplinary management of breast cancer. The prognostic impact of treatment response has been clearly demonstrated. However, the impact of treatment response on the indication for adjuvant radiotherapy is unclear. This review summarizes important implications of NACT and treatment response on the risk of recurrence and locoregional multidisciplinary management from the standpoint of radiation oncology.

Keywords: Neoadjuvant treatment; Neoplasm recurrence, local; Post-mastectomy radiotherapy; Regional nodal irradiation; Sentinel lymph node biopsy.

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References

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