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. 1985 Nov;56(2):651-4.
doi: 10.1128/JVI.56.2.651-654.1985.

Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines

Group B coxsackieviruses readily establish persistent infections in human lymphoid cell lines

D Matteucci et al. J Virol. 1985 Nov.

Abstract

Exposing human lymphoid cell lines to uncloned or recently cloned group B coxsackieviruses results in the frequent establishment of chronically infected cultures. Persistence is maintained by a carrier culture mechanism involving virus spread through the medium and replication among a minority of cells at any given time. These studies provide a model for persistence by highly cytocidal viruses.

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