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. 1985 Oct;35(5):473-6.

Reexamination of the efficacy of vaccination against mousepox

R M Buller, G D Wallace
  • PMID: 2997541

Reexamination of the efficacy of vaccination against mousepox

R M Buller et al. Lab Anim Sci. 1985 Oct.

Abstract

Experiments were conducted to evaluate the efficacy of three strains of vaccinia virus, IHD-T, Lister and Wyeth, to immunize the BALB/cByJ mouse against infection with ectromelia virus. Mice vaccinated with any of the strains were protected for at least 12 weeks against clinically apparent disease when challenged with cage-mates infected with a virulent stain (NIH-79) of ectromelia virus. However, 4 to 8 weeks after vaccination mice were capable of transmitting virus to non-vaccinated cage-mates. The results are discussed within the context of the current practices for preventing and controlling ectromelia epizootics.

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