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Editorial
. 2018 Aug;124(16):3290-3292.
doi: 10.1002/cncr.31574. Epub 2018 Jul 5.

Pragmatic approaches to address expansion cohort design

Suzanne E Dahlberg  1 , Robert J Gray  1
Affiliations
Editorial

Pragmatic approaches to address expansion cohort design

Suzanne E Dahlberg et al. Cancer. 2018 Aug.
No abstract available

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Conflict of interest statement

Conflicts of Interest: Dr. Dahlberg reports a position on a steering committee for clinical trial sponsored by AstraZeneca. Dr. Gray has nothing to disclose.

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References

    1. Dahlberg SE, Shapiro GI, Clark JW, Johnson BE. Evaluation of statistical designs in phase I expansion cohorts: the Dana-Farber/Harvard Cancer Center experience. J Natl Cancer Inst. 2014 Jun 24;106(7):dju163. doi: 10.1093/jnci/dju163. Print 2014 Jul. - DOI - PubMed
    1. Druker BJ, Sawyers CL, Kantarjian H, et al. Activity of a specific inhibitor of the BCR-ABL tyrosine kinase in the blast crisis of chronic myeloid leukemia and acute lymphoblastic leukemia with the Philadelphia chromosome. N Engl J Med. 2001;344(14):1038–1042. - PubMed
    1. Druker BJ, Talpaz M, Resta DJ, et al. Efficacy and safety of a specific inhibitor of the BCR-ABL tyrosine kinase in chronic myeloid leukemia. N Engl J Med. 2001;344(14):1031–1037. - PubMed
    1. Paez JG, Janne PA, Lee JC, et al. EGFR mutations in lung cancer: correlation with clinical response to gefitinib therapy. Science. 2004;304(5676):1497–1500. - PubMed
    1. Lynch TJ, Bell DW, Sordella R. Activating mutations in the epidermal growth factor receptor underlying responsiveness of non–small-cell lung cancer to gefitinib. N Engl J Med. 2004;350(21):2129–2139. - PubMed

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