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. 2018 Aug;10(8):630-635.
doi: 10.14740/jocmr3403w. Epub 2018 Jun 27.

Association Between Visceral Fat Accumulation and Exercise Tolerance in Non-Obese Subjects Without Diabetes

Miki Shioya-Yamada  1 , Kazunori Shimada  1   2   3 , Miho Nishitani-Yokoyama  2 , Eiryu Sai  2 , Kageumi Takeno  4 , Yoshifumi Tamura  3   4 , Hirotaka Watada  3   4 , Ryuzo Kawamori  3   4 , Hiroyuki Daida  2   3 , Sachio Kawai  1
Affiliations

Association Between Visceral Fat Accumulation and Exercise Tolerance in Non-Obese Subjects Without Diabetes

Miki Shioya-Yamada et al. J Clin Med Res. 2018 Aug.

Abstract

Background: We examined the associations between visceral fat accumulation, presence of the components of metabolic syndrome (MetS), and exercise tolerance in non-obese subjects without diabetes.

Methods: Seventy-four non-obese, non-diabetic Japanese men were enrolled. The subjects were divided into the following two groups: non-obese subjects without any MetS risk factors (n = 38, Group A) and non-obese subjects with one or two MetS risk factors (n = 36, Group B). Anthropometric and metabolic parameters were measured. The response of heart rate (HR) and blood pressure (BP), and exercise tolerance were also evaluated with a cardiopulmonary exercise test using a bicycle ergometer.

Results: The body mass index, abdominal circumference, visceral fat area, and homeostasis model assessment-insulin resistance, were significantly higher, while levels of anaerobic threshold and maximal oxygen uptake were significantly lower in Group B than in Group A. The levels of resting HR, resting BP, and BP at maximal exercise were significantly higher in Group B than in Group A. There were no significant differences in the HR at maximal exercise as well as the HR and BP after exercise between the two groups. The visceral fat area was significantly and negatively correlated with exercise tolerance. Multivariate linear regression analyses demonstrated that visceral fat area, but not abdominal circumference, was significantly and independently associated with maximal oxygen uptake.

Conclusions: These data suggest that the visceral fat area is a significant determinant for exercise tolerance even in non-obese subjects without diabetes.

Keywords: Exercise tolerance; Metabolic syndrome; Non-obese men; Visceral fat.

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Conflict of interest statement

None declared.

Figures

Figure 1
Figure 1
Correlation between the visceral fat area and maximum oxygen uptake. A significant inverse relationship was observed between the visceral fat area and maximum oxygen uptake in the non-obese subjects (r = -0.37, P < 0.01, n = 74).
See this image and copyright information in PMC

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