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Case Reports
. 2018 May 29;2018(5):rjy116.
doi: 10.1093/jscr/rjy116. eCollection 2018 May.

Pharmacobezoar-a rare case presented as gastric outlet obstruction

Sumita A Jain  1 , Lakshman Agarwal  1 , Anil Khyalia  1 , Pramod Chandolia  1 , Harish Kaknale  2
Affiliations
Case Reports

Pharmacobezoar-a rare case presented as gastric outlet obstruction

Sumita A Jain et al. J Surg Case Rep. .

Abstract

BEZOARS are retained concretions of indigestible foreign material that accumulate and conglomerate in the gastrointestinal tract, most commonly in the stomach. Prevalence of bezoar is 0.4%. Bezoars are classified in four categories: phytobezoars; trichobezoars; pharmacobezoars; lactobezoars. A 58-year-old man admitted with complains of pain abdomen and recurrent vomiting since last 3 months. Upper GI endoscopic biopsy reported-chronic gastritis with very occasional non-caseating epitheloid granuloma in lamina propria, no evidence of neoplasia? Crohn's disease. Keeping Crohn's as diagnosis patient was given mesalamine 400 mg tid by gastrophyscian. But patient did not respond so the patient was advised surgical management. Repeat UGI endoscopy revealed multiple pills (mesalamine) in the stomach with gastric outlet obstruction (GOO). Around 40 pills were extracted with the help of flower basket, and then patient develope GOO and underwent Laparoscopic gastrojejunostomy and truncal vagotomy.

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Figures

Figure 1:
Figure 1:
BMFT Film, reported multiple hyperplastic polyps with GOO.
Figure 2:
Figure 2:
UGI endoscopy showing multiple pills.
Figure 3:
Figure 3:
Gastrojejunostomy by endostaplers.
Figure 4:
Figure 4:
Left and right truncal vagotomy.
See this image and copyright information in PMC

References

    1. Andru CH, Ponskky JL. Bezoars: classification, pathophysiology, and treatment. Am J Gastroenterol 1988;83:476–8. - PubMed
    1. Escamilla C, Robles-Campos R, Parrilla-Paricio P, Lujan-Mompean J, Liron-Ruiz R, Torralba-Martinez JA. Intestinal obstruction and bezoars. J Am Coll Surg 1994;179:285–8. - PubMed
    1. Robles R, Parrilla P, Escamilla C, Lujan JA, Torralba JA, Liron R, et al. Gastrointestinal bezoars. Br J Surg 1994;81:1000–1. - PubMed
    1. Taylor JR, Streetman DS, Castle SS. Medication bezoars: a literature review and a report of a case. Ann Pharmacother 1998;32:940–6. - PubMed
    1. de Albuquerque IC, Carvalho MA, Betista RR, Formiga GJS. Bezoar by mesalamine tablet: cause of intestinal obstruction in Crohn’s disease. J Coloproctol (Rio J) 2012;32 (4:422-5).

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