Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 2018 May 4;5(6):ofy099.
doi: 10.1093/ofid/ofy099. eCollection 2018 Jun.

Provider Adherence to Pre-exposure Prophylaxis Monitoring Guidelines in a Large Primary Care Network

Matthew A Spinelli  1 , Hyman M Scott  1   2 , Eric Vittinghoff  3 , Albert Y Liu  2   4 , Alicia Morehead-Gee  4 , Rafael Gonzalez  2 , Susan P Buchbinder  2   3   4
Affiliations

Provider Adherence to Pre-exposure Prophylaxis Monitoring Guidelines in a Large Primary Care Network

Matthew A Spinelli et al. Open Forum Infect Dis. .

Abstract

Insufficient pre-exposure prophylaxis (PrEP) laboratory monitoring could increase HIV resistance and sexually transmitted infections. We examined test-ordering in a primary care network. Providers did not order HIV testing before almost one-quarter of PrEP initiations; panel management was associated with higher testing. Effective monitoring is needed to maximize PrEP's preventive impact.

Keywords: HIV; behavioral disinhibition; pre-exposure prophylaxis; renal insufficiency; sexually transmitted infections.

PubMed Disclaimer

References

    1. Grant RM, Lama JR, Anderson PL, et al. iPrEx Study Team Preexposure chemoprophylaxis for HIV prevention in men who have sex with men. N Engl J Med 2010; 363:2587–99. - PMC - PubMed
    1. Harawa NT, Holloway IW, Leibowitz A, et al. Serious concerns regarding a meta-analysis of preexposure prophylaxis use and STI acquisition. AIDS 2017; 31:739–40. - PMC - PubMed
    1. Dimitrov DT, Boily MC, Hallett TB, et al. How much do we know about drug resistance due to PrEP use? Analysis of experts’ opinion and its influence on the projected public health impact. PLoS One 2016; 11:e0158620. - PMC - PubMed
    1. Beymer MR, DeVost MA, Weiss RE, et al. Does HIV pre-exposure prophylaxis use lead to a higher incidence of sexually transmitted infections? A case-crossover study of men who have sex with men in Los Angeles, California. Sex Transm Infect. In press. - PMC - PubMed
    1. Liu AY, Cohen SE, Vittinghoff E, et al. Preexposure prophylaxis for HIV infection integrated with municipal- and community-based sexual health services. JAMA Intern Med 2016; 176:75–84. - PMC - PubMed