doi: 10.1126/science.2997921.
A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients
- PMID: 2997921
- DOI: 10.1126/science.2997921
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A new HTLV-III/LAV encoded antigen detected by antibodies from AIDS patients
Science.
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Abstract
A newly identified protein from HTLV-III/LAV, the virus implicated as the etiologic agent of the acquired immune deficiency syndrome, was studied. This protein, which has a molecular weight of 27,000 (p27), was shown by amino acid sequencing to have a coding origin 3' to the env gene on the HTLV-III genome. The presence of antibodies to p27 in virus-exposed individuals indicated that this gene is functional in the natural host.
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