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Comment
. 2018 Jul 5;23(1):13-14.
doi: 10.1016/j.stem.2018.06.012.

Recipes for Making Neurons using Combinatorial Forward Genetics

Vania Broccoli  1 , Mirko Luoni  2
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Recipes for Making Neurons using Combinatorial Forward Genetics

Vania Broccoli et al. Cell Stem Cell. .
Free article

Abstract

In a recent issue of Nature, Tsunemoto et al. (2018) perform a systematic screening to identify several transcription factor pairs able to generate a variety of different induced neuronal cell populations that share a core neuronal signature, yet differ for specific molecular features.

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  • Diverse reprogramming codes for neuronal identity.
    Tsunemoto R, Lee S, Szűcs A, Chubukov P, Sokolova I, Blanchard JW, Eade KT, Bruggemann J, Wu C, Torkamani A, Sanna PP, Baldwin KK. Tsunemoto R, et al. Nature. 2018 May;557(7705):375-380. doi: 10.1038/s41586-018-0103-5. Epub 2018 May 9. Nature. 2018. PMID: 29743677 Free PMC article.

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