Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Nov 15;57(22):3329-3332.
doi: 10.2169/internalmedicine.1031-18. Epub 2018 Jul 6.

Successful Empiric Therapy for Postsplenectomy Sepsis with Campylobacter fetus in an Abattoir Worker with Follicular Lymphoma

Hideyuki Nakazawa  1   2 , Sayaka Nishina  1   2 , Hitoshi Sakai  1   2 , Toshiro Ito  2 , Fumihiro Ishida  1   3 , Kiyoshi Kitano  2
Affiliations
Case Reports

Successful Empiric Therapy for Postsplenectomy Sepsis with Campylobacter fetus in an Abattoir Worker with Follicular Lymphoma

Hideyuki Nakazawa et al. Intern Med. .

Abstract

Asplenia may yield an increased risk of fulminant sepsis with various pathogens. Human infection with Campylobacter fetus is rare, but it often presents with non-gastrointestinal tract infection among immunocompromised individuals. A 55-year-old abattoir worker presented with a fever. He had had splenectomy for follicular lymphoma and rituximab maintenance therapy by four months before the presentation. Blood cultures yielded C. fetus, and the administration of meropenem dissolved the bacteremia. Further maintenance therapy was withheld, and no recurrence of infection has been observed for seven years. Asplenia, occupational exposure, and/or rituximab maintenance therapy might have been precipitating factors of this rare infection.

Keywords: Campylobacter fetus; abattoir; follicular lymphoma; rituximab; sepsis; splenectomy.

PubMed Disclaimer

Figures

Figure.
Figure.
Enhanced computed tomography showed that the ascending colon (arrow heads) was edematous.
See this image and copyright information in PMC

References

    1. Rubin LG, Schaffner W. Clinical practice. Care of the asplenic patient. N Engl J Med 371: 349-356, 2014. - PubMed
    1. Nakazawa H, Makishima H, Ito T, et al. . Screening tests using serum tissue transglutaminase IgA may facilitate the identification of undiagnosed celiac disease among Japanese population. Int J Med Sci 11: 819-823, 2014. - PMC - PubMed
    1. Waghorn DJ. Overwhelming infection in asplenic patients: current best practice preventive measures are not being followed. J Clin Pathol 54: 214-218, 2001. - PMC - PubMed
    1. Moberley S, Holden J, Tatham DP, Andrews RM. Vaccines for preventing pneumococcal infection in adults. Cochrane Database Syst Rev Cd000422, 2013. - PMC - PubMed
    1. O'Neal HR Jr, Niven AS, Karam GH. Critical illness in patients with asplenia. Chest 150: 1394-1402, 2016. - PubMed

Publication types

MeSH terms