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Review
. 2018 Jun 1;36(3):319-324.
doi: 10.7518/hxkq.2018.03.017.

[Pharmacokinetics and drug safety of oral infectious disease during pregnancy]

[Article in Chinese]
Hong-Yu Li  1 , Ya-Chuan Zhou  1 , Xue-Dong Zhou  1 , Li-Wei Zheng  1
Affiliations
Review

[Pharmacokinetics and drug safety of oral infectious disease during pregnancy]

[Article in Chinese]
Hong-Yu Li et al. Hua Xi Kou Qiang Yi Xue Za Zhi. .

Abstract
in English, Chinese

Pregnancy is a time of particular vulnerability in terms of physiologic changes resulting in higher risk of oral infectious diseases. There is emerging evidence showing that irrational dental treatment and drug therapy are associated with adverse pregnancy outcomes, including infant malformation or spontaneous abortion. This article reviews the pharmacokinetics of medications in pregnant women and the fetus and introduces a guideline for drug therapy and common dental drugs used during pregnancy.

妊娠期妇女因其所处生理阶段的特殊性，各项生理指标会有所变化，发生口腔疾病的风险急剧增加，对口腔感染性疾病不及时治疗或不合理用药可能会导致胎儿畸形甚至流产。本文对妊娠期药物动力学改变、妊娠期用药原则及治疗口腔感染性疾病常用药物进行综述，为口腔科医生对处于妊娠期口腔感染性疾病患者安全用药提供参考。.

Keywords: medication; oral health; pharmacokinetics; pregnancy.

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