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Review
. 2018 Aug;111(8):270-275.
doi: 10.1177/0141076818781406. Epub 2018 Jul 9.

Improbable, but plausible, research study: a randomised controlled trial of premature cord clamping vs. neonatal venesection to achieve routine prophylactic neonatal red cell reduction

Andrew Weeks  1 , Susan Bewley  2
Affiliations
Review

Improbable, but plausible, research study: a randomised controlled trial of premature cord clamping vs. neonatal venesection to achieve routine prophylactic neonatal red cell reduction

Andrew Weeks et al. J R Soc Med. 2018 Aug.
No abstract available

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Figures

Figure 1.
Figure 1.
Solid lines showing difference in neonatal haemoglobin with and without premature cord clamping. Derived from McDonald and Middleton. The light blue histogram data are derived from Liverpool Women’s Hospital statistics of all term babies admitted to the neonatal intensive care unit in 2005–2010 at a time when routine premature cord clamping was practised. The graph shows the spread of values of term babies in a unit where routine prophylactic neonatal volume depletion is practised via premature cord clamping (black line) vs. physiological cord management (dark blue line shows the expected haemoglobin levels derived from Cochrane meta-analysis showing a mean difference of 2.2 g/dL Hb in term babies; McDonald and Middleton).
Figure 2.
Figure 2.
Newborn baby receiving visible venesection on first day of life (Intervention group) aiming to remove a controlled and calculated fifth of the total blood volume based on birth weight.
See this image and copyright information in PMC

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