Comment on

• p53 inhibits CRISPR-Cas9 engineering in human pluripotent stem cells.

  Ihry RJ, Worringer KA, Salick MR, Frias E, Ho D, Theriault K, Kommineni S, Chen J, Sondey M, Ye C, Randhawa R, Kulkarni T, Yang Z, McAllister G, Russ C, Reece-Hoyes J, Forrester W, Hoffman GR, Dolmetsch R, Kaykas A. Ihry RJ, et al. Nat Med. 2018 Jul;24(7):939-946. doi: 10.1038/s41591-018-0050-6. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892062
• CRISPR-Cas9 genome editing induces a p53-mediated DNA damage response.

  Haapaniemi E, Botla S, Persson J, Schmierer B, Taipale J. Haapaniemi E, et al. Nat Med. 2018 Jul;24(7):927-930. doi: 10.1038/s41591-018-0049-z. Epub 2018 Jun 11. Nat Med. 2018. PMID: 29892067