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Case Reports
. 2018 Jun 10;13(4):810-814.
doi: 10.1016/j.radcr.2018.04.021. eCollection 2018 Aug.

Giant retroperitoneal schwannoma in a 52-year-old man

Taiyou L Harada  1 , Go Nagao  2 , Teiichiro Aoyagi  2 , Isao Kuroda  2 , Naoto Tokuyama  2 , Masahide Takahashi  1 , Yuri Takahashi  1 , Yukio Morishita  3 , Sugahara Shinji  1
Affiliations
Case Reports

Giant retroperitoneal schwannoma in a 52-year-old man

Taiyou L Harada et al. Radiol Case Rep. .

Abstract

Schwannoma in the retroperitoneal space is rare, and it is extremely rare in patients with no history of neurofibromatosis. We present a case of giant retroperitoneal schwannoma in a 52-year-old man who did not have neurofibromatosis. Because malignant transformation would be extremely rare in this circumstance, close imaging follow-up could avert the necessity for complete resection. The possibility of schwannoma should be considered when evaluating retroperitoneal tumors with the characteristic findings, even if there is no connection between the tumor and the intervertebral foramina.

Keywords: CT; MRI; Malignancy; Open biopsy; Retroperitoneal tumor; Schwannoma.

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Figures

Fig 1
Figs. 1-2
Computed tomography revealed that the retroperitoneal tumor consisted of three circumscribed round and oval tumors, extending craniocaudally with a slightly low density compared with muscle, and a maximum diameter of 130 mm.
Fig 2
Figs. 3-6
Magnetic resonance imaging revealed that the tumor was heterogeneous, and that it consisted of two compartments: a compartment with heterogeneous, high signal intensity on T2-weighted imaging (Fig. 3) with restricted diffusion (Figs. 4 and 5) and strong enhancement (Fig. 6), indicating a solid compartment; and the other compartment with very high signal intensity on T2-weighted imaging with no enhancement, indicating a cystic compartment.
Fig 3
Fig. 7
Ultrasonography showed a circumscribed hyperechoic mass with echo lucent inside the mass, indicating a cystic component.
Fig 4
Fig. 8
Open biopsy revealed a white circumscribed tumor, and leakage of mucinous liquid from inside, after cutting the tumor.
Fig 5
Fig. 9
Pathologic diagnosis based upon hematoxylin and eosin staining showed two compartments: compact hypercellular Antoni A areas and myxoid hypocellular Antoni B areas.
Fig 6
Fig. 10
Strong expression of S-100 protein was observed.
See this image and copyright information in PMC

References

    1. Wong C.S., Chu T.Y.C., Tam K.F. Retroperitoneal schwannoma: a common tumour in an uncommon site. Hong Kong Med J. 2010;16:66–68. - PubMed
    1. Felix E.L., Wood D.K., Das Gupta T.K. Tumors of the retroperitoneum. Curr Prob Cancer. 1981;6:1–47. - PubMed
    1. Okuyama T., Tagaya N., Saito K., Takahashi S., Shibusawa H., Oya M. Laparoscopic resection of a retroperitoneal pelvic schwannoma. J Surg Case Rep. 2014;2014(1):rjt122. - PMC - PubMed
    1. Pilavaki M., Chourmouzi D., Kiziridou A., Skordalaki A., Zarampouzas T., Dervelengas A. Imaging of peripheral nerve sheath tumors with pathologic correlation: pictorial review. Eur J Radiol. 2004;52:229–239. - PubMed
    1. Goh B.K., Tan Y.M., Chung Y.F., Chow P.K., Ooi L.L., Wong W.K. Retroperitoneal schwannoma. Am J Surg. 2006;192:14–18. - PubMed

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