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. 2018 Jun 29;10(1):7546.
doi: 10.4081/dr.2018.7486. eCollection 2018 Apr 23.

A case of lipomembranous panniculitis with a dramatic response to the treatment of venous insufficiency

Didem Mullaaziz  1 , Aslı Kaptanoğlu  2 , Emel Erdal Çalıkoğlu  1 , Hanife Özkayalar  3
Affiliations

A case of lipomembranous panniculitis with a dramatic response to the treatment of venous insufficiency

Didem Mullaaziz et al. Dermatol Reports. .

Abstract

Lipomembranous panniculitis (LP) is a peculiar type of fat necrosis and is reported with various clinical conditions, mostly with peripheral vascular diseases. Here, a case of a 57-year-old woman with a painful erythematous swelling of the right leg in association with venous insufficiency has been reported. Although LP is frequently associated with venous insufficiency, to the best of our knowledge, this is the first report on the beneficial effect of venous insufficiency treatment in LP.

Keywords: Lipomembranous panniculitis; fat necrosis; panniculitis; venous insufficiency.

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Conflict of interest statement

Conflict of interest: the authors declare no potential conflict of interest.

Figures

Figure 1.
Figure 1.
Erythematous, indurated sclerotic plaque on the posterolateral aspect of the right tibia.
Figure 2.
Figure 2.
The subcutaneous fat had microcystic changes within the fat.
Figure 3.
Figure 3.
The membrane formed small pseudopapillae (PAS x20).
Figure 4.
Figure 4.
Macrophage accumulation was found inthe subcutaneous tissue (HE X20).
Figure 5.
Figure 5.
Fibrozis was found in reticular dermis (HE X 10).
Figure 6.
Figure 6.
After 6 months of treatment.
See this image and copyright information in PMC

References

    1. Gouveia C, Soares Almeida LM. [Lipomembranous panniculitis: clinicopathologic correlation of 8 cases]. [Article in Spanish]. Actas Dermosifiliogr 2006;97:379-84. - PubMed
    1. Al-Brahim N, Ceballos K, Sur M, et al. Lipomembranous panniculitis: report of a case. Ann Diagn Pathol 2007;11:282-4. - PubMed
    1. Alegre VA, Winkelmann K, Aliaga A. Lipomembranous changes in chronic panniculitis. J Am Acad Dermatol 1988;19:39-46. - PubMed
    1. Asadi-Kani Z, Moravvej H, Gaisari M, Kavand S, Saeedi M. A Case of Lipomembranous Panniculitis Associated with Rheumatoid Arthritis. Iran J Dermatol 2009;12:27-9.
    1. Snow JL, Su WP. Lipomembranous (membranocystic) fat necrosis. Clinicopathologic correlation of 38 cases. Am J Dermatopathol 1996;18:151-5. - PubMed

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