Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Case Reports
. 2018 Jun 11:2018:4854368.
doi: 10.1155/2018/4854368. eCollection 2018.

Giant Adrenal Myelolipoma in a Patient without Endocrine Disorder: A Case Report and a Review of the Literature

Yoshifumi Nakayama  1   2 , Nobutaka Matayoshi  1 , Masaki Akiyama  1   2 , Yusuke Sawatsubashi  1   2 , Jun Nagata  1   2 , Masanori Hisaoka  3 , Keiji Hirata  1
Affiliations
Case Reports

Giant Adrenal Myelolipoma in a Patient without Endocrine Disorder: A Case Report and a Review of the Literature

Yoshifumi Nakayama et al. Case Rep Surg. .

Abstract

We herein present a surgically treated case of huge adrenal myelolipoma. A 62-year-old woman presented to our surgical outpatient clinic with a retroperitoneal tumor. A clinical examination revealed an elastic soft, smooth-surfaced, painless, child-head-sized tumor with poor mobility, which was located in the left upper abdomen. Computed tomography (CT) and magnetic resonance imaging (MRI) of the abdomen revealed an uneven tumor surrounding the stomach, spleen, pancreas, and left kidney, which was 20 × 18 × 10 cm in size. The retroperitoneal tumor was resected. The tumor was attached to the surrounding organs, including the pancreas, spleen, and left kidney, but had not directly invaded these organs. The tumor was yellow and elastic soft and covered with a thin film. The origin of the tumor was suggested to be the left adrenal gland. The weight of the excised tumor was 1500 g. The histopathological diagnosis was adrenal myelolipoma. The patient had an uneventful recovery and was discharged from the hospital on the thirteenth day after the operation. She has been followed up in our outpatient clinic.

PubMed Disclaimer

Figures

Figure 1
Figure 1
Abdominal computed tomography (CT) demonstrated a child-head-sized mass with heterogeneous contrast located in the left upper abdomen around the stomach, spleen, pancreas, and left kidney on the horizontal (a) and coronal (b) images.
Figure 2
Figure 2
Magnetic resonance imaging (MRI) revealed a heterogeneously hyperintense mass on T1-weighted imaging (a), a relatively uniform and hyperintense mass on T2-weighted imaging (b), and a hypointense mass with an enhanced border on Gd-enhanced imaging (c).
Figure 3
Figure 3
The operative findings revealed a yellow mass covered with a thin layer that was located at the left side of the stomach, posteriorly to the transverse mesocolon and pancreas, on the cranial side of the left kidney.
Figure 4
Figure 4
An examination of the cut surface of this tumor revealed a multilobular yellow mass with bleeding in places.
Figure 5
Figure 5
A histopathological examination (×200) with hematoxylin and eosin staining revealed that tumor was composed of a proliferation of mature and variable-sized adipocytes admixed with aggregates of hematopoietic elements.
See this image and copyright information in PMC

Similar articles

See all similar articles

Cited by

References

    1. Olsson C. A., Krane R. J., Klugo R. C., Selikowitz S. M. Adrenal myelolipoma. Surgery. 1973;73(5):665–670. - PubMed
    1. Wagnerová H., Lazúrová I., Bober J., Sokol L., Zachar M. Adrenal myelolipoma. 6 cases and a review of the literature. Neoplasma. 2004;51(4):300–305. - PubMed
    1. Yildiz L., Akpolat I., Erzurumlu K., Aydin O., Kandemir B. Giant adrenal myelolipoma: case report and review of the literature. Pathology International. 2000;50(6):502–504. doi: 10.1046/j.1440-1827.2000.01071.x. - DOI - PubMed
    1. Daneshmand S., Quek M. L. Adrenal myelolipoma: diagnosis and management. Urology Journal. 2006;3(2):71–74. - PubMed
    1. Nermoen I., Rørvik J., Holmedal S. H., et al. High frequency of adrenal myelolipomas and testicular adrenal rest tumours in adult Norwegian patients with classical congenital adrenal hyperplasia because of 21-hydroxylase deficiency. Clinical Endocrinology. 2011;75(6):753–759. doi: 10.1111/j.1365-2265.2011.04151.x. - DOI - PubMed

Publication types

LinkOut - more resources