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Review
. 2017 Nov 29;8(3):361-376.
doi: 10.1016/j.jtcme.2017.08.012. eCollection 2018 Jul.

An update on natural compounds in the remedy of diabetes mellitus: A systematic review

Hira Choudhury  1 , Manisha Pandey  1 , Chua Kui Hua  1 , Cheah Shi Mun  1 , Jessmie Koh Jing  1 , Lillian Kong  1 , Liang Yee Ern  1 , Nik Ahmad Ashraf  1 , Soohg Wai Kit  1 , Tan Sin Yee  1 , Mallikarjuna Rao Pichika  1 , Bapi Gorain  2 , Prashant Kesharwani  1   3
Affiliations
Review

An update on natural compounds in the remedy of diabetes mellitus: A systematic review

Hira Choudhury et al. J Tradit Complement Med. .

Abstract

Herbal medicine, phytomedicine or botanical medicine are synonymous, utilizes plants intended for medicinal purposes. Medicinal use of herbal medicine in the treatment and prevention of diseases including diabetes has a long history compared to conventional medicine. Diabetes is one of the major public health concerns over the world. Diabetes or hyperglycemia is considered to be one of the common public health hazard; optimal control of which is still not possible. Persistent hyperglycemia or uncontrolled diabetes has the potential to cause serious complications such as kidney disease, vision loss, cardiovascular disease, and lower-limb amputations which contributed towards morbidity and mortality in diabetes. There are various approaches to treat and prevent diabetes as well as its secondary complications, one of it is herbal medicines. However, the selection of herbs might depends on several factors, which include the stage of progression of diabetes, types of comorbidities that the patients are having, availability, affordability as well as the safety profile of the herbs. This review focuses on the herbal and natural remedies that play the role in the treatment or prevention of this morbid disorder - diabetes, including their underlying mechanisms for the blood glucose-lowering property and the herbal products already been marketed for the remedial action of diabetes.

Keywords: Active component; Diabetes control; Herbal medicine; Insulin resistivity; Insulin secretion.

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Figures

Image 1
Graphical abstract
Fig. 1
Fig. 1
The traditional utilization of herbal medicines in different field of medical field.
Fig. 2
Fig. 2
Condition to develop diabetic mellitus disease and herbal approaches in the improvement of insulin secretion or improvement in insulin resistivity of the body cells.
Fig. 3
Fig. 3
Mechanism of actions of different anti-diabetic agents in the treatment of high glucose level in the circulation.
See this image and copyright information in PMC

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