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Case Reports
. 2018 Aug;61(8):883-886.
doi: 10.1097/DCR.0000000000001139.

Neoadjuvant Therapy for Rectal Cancer

Ira L Leeds  1 , Sandy H Fang
Affiliations
Case Reports

Neoadjuvant Therapy for Rectal Cancer

Ira L Leeds et al. Dis Colon Rectum. 2018 Aug.

Abstract

A 63-year-old man presents to his primary care doctor with a one-month history of blood in his stools. He is referred for a colonoscopy and found to have a friable mass along the anterior wall just proximal to the second rectal fold. A biopsy confirms moderately-differentiated adenocarcinoma. The patient then obtains pelvic magnetic resonance imaging and chest, abdomen, and pelvis computed tomography demonstrating local invasion of the primary tumor into the mesorectal fat (T3), no suspicious regional lymph nodes (N0), and no evidence of distant metastatic disease (M0).

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Conflict of interest statement

Conflicts of Interest: None

Figures

Figure 1
Figure 1
Neoadjuvant-eligible staging findings using pelvic magnetic resonance imaging. A) T3 midrectal lesion with posterior invasion through the muscularis propria (low intensity signal encircling rectum) into the mesorectal fat with arrows marking lateral extent. B) T2 mid-rectal, posterior lesion with thinning of the muscularis propria and a 5mm pathologic lymph node (arrow) located in the posterior mesorectal fat.
Figure 2
Figure 2
Evaluation and treatment algorithm for neoadjuvant-eligible rectal cancer.
See this image and copyright information in PMC

References

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