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. 1977 Feb 25;195(4280):787-9.
doi: 10.1126/science.299957.

Ribavirin: efficacy in the treatment of murine autoimmune disease

L W Klassen, D R Budman, G W Williams, A D Steinberg, N L Gerber

Ribavirin: efficacy in the treatment of murine autoimmune disease

L W Klassen et al. Science. .

Abstract

Ribavirin, a drug with known antiviral activity, was given to mice with established lupus nephritis. Ribavirin was effective in prolonging survival, reducing the titer of antibodies to DNA, and reversing proteinuria. Other antiviral agents were not effective in the dosages used.

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