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Review
. 2018 Jun;7(3):301-307.
doi: 10.21037/gs.2018.04.04.

Evaluation of skin viability in nipple sparing mastectomy (NSM)

Affiliations
Review

Evaluation of skin viability in nipple sparing mastectomy (NSM)

Michael R Zenn. Gland Surg. 2018 Jun.

Abstract

Nipple sparing mastectomy (NSM) is quickly becoming the standard of care due to earlier stage of breast cancer diagnosis, increased prevalence of prophylactic mastectomies, improved surgical techniques, and the desire of women to keep their nipples. However, the procedure is plagued with problems of nipple and skin necrosis due to the inherent ischemic nature of mastectomy. Indocyanine green (ICG) technologies offer surgeons new information that is helpful in the battle to reduce these devastating complications.

Keywords: Nipple sparing mastectomy (NSM); indocyanine green (ICG); necrosis.

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Conflict of interest statement

Conflicts of Interest: Dr. MR Zenn was Chief Medical Officer for Novadaq (SPY technology) 2016–2017, is a consultant for Stryker, and receives royalties from QMP (DVDs, app) and Thieme (textbook).

Figures

Figure 1
Figure 1
A clinical example of SPY’s predictive value. Areas in dark blue on the left were predicted to necrose but the clinical judgment was to leave the skin. The SPY distribution mirrors the areas of ischemia and necrosis seen on the right.
Figure 2
Figure 2
A clinical example of a Zenn Delay, pictured on the left deflated, at 2 weeks after mastectomy and ready for direct-to-implant reconstruction. On the right, 2 months postoperative from a one stage, ADM-supported (DermACELL 16 cm × 20 cm) round smooth silicone gel implant (Mentor) breast reconstruction. Note the nature ptosis and correct nipple position obtainable without intervening months of tissue expansion.

References

    1. Komorowska-Timek E, Gurtner GC. Intraoperative perfusion mapping with laser-assisted indocyanine green imaging can predict and prevent complications in immediate breast reconstruction. Plast Reconstr Surg 2010;125:1065-73. 10.1097/PRS.0b013e3181d17f80 - DOI - PubMed
    1. Sood M, Glat P. Potential of the SPY intraoperative perfusion assessment system to reduce ischemic complications in immediate postmastectomy breast reconstruction. Ann Surg Innov Res 2013;7:9. 10.1186/1750-1164-7-9 - DOI - PMC - PubMed
    1. Garvey PB, Buchel EW, Pockaj BA, et al. DIEP and pedicled TRAM flaps: a comparison of outcomes. Plast Reconstr Surg 2006;117:1711-9; discussion 1720-1. - PubMed
    1. Spear SL, Ducic I, Cuoco F, et al. The effect of smoking on flap and donor-site complications in pedicled TRAM breast reconstruction. Plast Reconstr Surg 2005;116:1873-80. 10.1097/01.prs.0000191200.81375.8c - DOI - PubMed
    1. Pestana IA, Coan B, Erdmann D, et al. Early experience with fluorescent angiography in free-tissue transfer reconstruction. Plast Reconstr Surg 2009;123:1239-44. 10.1097/PRS.0b013e31819e67c1 - DOI - PubMed

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