Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018;14(4):212-218.
doi: 10.2174/1573396314666180712114531.

Neonatal and Long-Term Consequences of Fetal Growth Restriction

Affiliations
Review

Neonatal and Long-Term Consequences of Fetal Growth Restriction

Marina Colella et al. Curr Pediatr Rev. 2018.

Abstract

Background: Fetal Growth Restriction (FGR) is one of the most common noxious antenatal conditions in humans, inducing a substantial proportion of preterm delivery and leading to a significant increase in perinatal mortality, neurological handicaps and chronic diseases in adulthood. This review summarizes the current knowledge about the postnatal consequences of FGR, with a particular emphasis on the long-term consequences on respiratory, cardiovascular and neurological structures and functions.

Result and conclusion: FGR represents a global health challenge, and efforts are urgently needed to improve our understanding of the critical factors leading to FGR and subsequent insults to the developing organs.

Keywords: FGR; diseases; long-term handicap; maternal malnutrition; neonatal brain injury; perinatal mortality..

PubMed Disclaimer

References

    1. Jarvis S., Glinianaia S.V., Torrioli M-G., et al. Cerebral palsy and intrauterine growth in single births: European collaborative study. Lancet. 2003;362(9390):1106–1111. - PubMed
    1. Gordijn S.J., Beune I.M., Ganzevoort W. Building consensus and standards in fetal growth restriction studies. Best Pract. Res. Clin. Obstet. Gynaecol. 2018;49:117–126. - PubMed
    1. Lausman A., Kingdom J., Gagnon R., et al. Intrauterine growth restriction: screening, diagnosis, and management. J. Obstet. Gynaecol. Can. 2013;35(8):741–748. - PubMed
    1. de Onis M., Blössner M., Villar J. Levels and patterns of intrauterine growth retardation in developing countries. Eur. J. Clin. Nutr. 1998;52(Suppl. 1):S5–S15. - PubMed
    1. Frøen J.F., Gardosi J.O., Thurmann A., Francis A., Stray-Pedersen B. Restricted fetal growth in sudden intrauterine unexplained death. Acta Obstet. Gynecol. Scand. 2004;83(9):801–807. - PubMed