Review
Nonoxynol-9
In: Drugs and Lactation Database (LactMed®) [Internet]. Bethesda (MD): National Institute of Child Health and Human Development; 2006.
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- PMID: 29999743
- Bookshelf ID: NBK500684
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Review
Nonoxynol-9
Excerpt
Nonoxynol-9 is a relatively nontoxic nonionic surfactant and only trivial amounts of the drug have been found in the milk of animals after vaginal administration.[1] Limited information indicates that breastfed infants of mothers using vaginal nonoxynol-9 experienced no adverse effects. Vaginal use of nonoxynol-9 is acceptable in nursing mothers.
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References
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- Johnson W, Jr. Final report on the safety assessment of octoxynol-1, octoxynol-3, octoxynol-5, octoxynol-6, octoxynol-7, octoxynol-8, octoxynol-9, octoxynol-10, octoxynol-11, octoxynol-12, octoxynol-13, octoxynol-16, octoxynol-20, octoxynol-25, octoxynol-30, octoxynol-33, octoxynol-40, octoxynol-70, octoxynol-9 carboxylic acid, octoxynol-20 carboxylic acid, potassium octoxynol-12 phosphate, sodium octoxynol-2 ethane sulfonate, sodium octoxynol-2 sulfate, sodium octoxynol-6 sulfate, and sodium octoxynol-9 sulfate. Int J Toxicol 2004;23 Suppl 1:59-111. - PubMed
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- Peralta O, Díaz S, Juez G, et al. Fertility regulation in nursing women: V. Long-term influence of a low-dose combined oral contraceptive initiated at day 90 postpartum on lactation and infant growth. Contraception 1983;27:27-38. - PubMed
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