Rosuvastatin
- PMID: 30000421
- Bookshelf ID: NBK501362
Rosuvastatin
Excerpt
Levels of rosuvastatin in milk are low, and one case of an older infant breastfed during maternal rosuvastatin therapy found no adverse effects. The consensus opinion is that women taking a statin should not breastfeed because of a concern with disruption of infant lipid metabolism. However, others have argued that children homozygous for familial hypercholesterolemia are treated with statins beginning at 1 year of age, that statins have low oral bioavailability, and risks to the breastfed infant are low, especially with rosuvastatin and pravastatin.[1] Until more data become available, an alternate drug may be preferred, especially while nursing a newborn or preterm infant.
References
-
- Holmsen ST, Bakkebo T, Seferowicz M, et al. Statins and breastfeeding in familial hypercholesterolaemia. Tidsskr Nor Laegeforen 2017;137:686–7. - PubMed
-
- Schutte AE, Symington EA, du Preez, JL. Rosuvastatin is transferred into human breast milk: A case report. Am J Med 2013;126:e7–8. - PubMed
-
- Karatekin Ş, Şenol E. Neurodevelopmental and growth follow-up of an infant exposed to rosuvastatin by lactation: A case report. Breastfeed Med 2025;20:453–5. - PubMed
-
- Oteri A, Catania MA, Travaglini R, et al. Gynecomastia possibly induced by rosuvastatin. Pharmacotherapy 2008;28:549–51. - PubMed
Publication types
LinkOut - more resources
Full Text Sources