The structural gene for aldolase B (ALDB) maps to 9q13----32
- PMID: 3000275
- DOI: 10.1111/j.1469-1809.1985.tb01691.x
The structural gene for aldolase B (ALDB) maps to 9q13----32
Abstract
We used a cloned cDNA probe for the B subunit of human aldolase (ALDB) and Southern blotting techniques to analyse DNA from a series of rodent X human somatic cell hybrids for the presence of specific ALDB-related sequences. Our results provide evidence for the assignment of the gene for ALDB to chromosome 9. Moreover, by direct gene dosage determination in two patients with chromosome 9 unbalanced rearrangements and by in situ hybridization we refined the regional chromosomal assignment to 9q13----q32 and most probably to 9q21.3----9q22.2.
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