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Case Reports
. 1985 Jul;49(3):173-80.
doi: 10.1111/j.1469-1809.1985.tb01691.x.

The structural gene for aldolase B (ALDB) maps to 9q13----32

I Henry, P Gallano, C Besmond, D Weil, M G Mattei, C Turleau, J Boué, A Kahn, C Junien
Case Reports

The structural gene for aldolase B (ALDB) maps to 9q13----32

I Henry et al. Ann Hum Genet. 1985 Jul.

Abstract

We used a cloned cDNA probe for the B subunit of human aldolase (ALDB) and Southern blotting techniques to analyse DNA from a series of rodent X human somatic cell hybrids for the presence of specific ALDB-related sequences. Our results provide evidence for the assignment of the gene for ALDB to chromosome 9. Moreover, by direct gene dosage determination in two patients with chromosome 9 unbalanced rearrangements and by in situ hybridization we refined the regional chromosomal assignment to 9q13----q32 and most probably to 9q21.3----9q22.2.

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