Successful use of adipose-derived mesenchymal stem cells to correct a male breast affected by Poland Syndrome: a case report

Abstract

Poland syndrome is a rare congenital anomaly in which affected persons are born with missing or underdeveloped muscles on one side of the body. In this case study we present the case of a 28-year-old male with absence of all middle phalanges of the right hand and other rare anomalies, who underwent reconstruction with a new method that combines a mixture of adipose-derived mesenchymal stem cells and fat transfer. The patient's restoration of the pectoralis area was aesthetically successful with no complications and remained unchanged even after 3.5 years. The proposed method represents an interesting reconstructive approach for treating Poland's syndrome deformities.

Figure 1:

Photo showing the 28-year-old male with absence of all middle phalanges of the right hand and other rare anomalies due to Poland Syndrome. Preoperative view appearance.

Figure 2:

Serial photos showing the changes between 2 months after the first surgery and 3.5 year follow-up: (a–c) View 2 months after the first surgery. (d) View 4 months after the first surgery. (e) 8 months after the first surgery. (f) View 7 months after the second surgery. (g) View 3.5 years after the reconstructive procedure.

Figure 3:

Serial soft tissue thoracic ultrasound photos 3.5 years after the first surgery indicating no pathologic findings.