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. 1985 Nov 1;231(3):769-71.
doi: 10.1042/bj2310769.

The effect of polar head group substitution on phospholipid methylation and the beta-adrenergic response in C6 glial cells

R C McKenzie, C S Gillespie, P J Brophy

The effect of polar head group substitution on phospholipid methylation and the beta-adrenergic response in C6 glial cells

R C McKenzie et al. Biochem J. .

Abstract

The membranes of intact C6 cells were enriched with phosphatidyldimethylethanolamine or phosphatidylmonomethylethanolamine. These cells showed enhanced rates of phospholipid methylation but this was not accompanied by an increased beta-adrenergic response. We conclude that phospholipid methylation is not coupled to the activation of adenylate cyclase in the beta-adrenergic response of C6 glial cells.

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