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. 2018 Aug 15;9(8):4100-4106.
doi: 10.1039/c8fo00956b.

The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging

A Cortés-Martín  1 , R García-Villalba, A González-Sarrías, M Romo-Vaquero, V Loria-Kohen, A Ramírez-de-Molina, F A Tomás-Barberán, M V Selma, J C Espín
Affiliations

The gut microbiota urolithin metabotypes revisited: the human metabolism of ellagic acid is mainly determined by aging

A Cortés-Martín et al. Food Funct. .

Abstract

Understanding individuals' response to dietary bioactives is crucial for personalized nutrition. We report here for the first time in a Caucasian cohort (5-90 years, n = 839) that aging is the main factor that determines the gut microbiota involved in the ellagic acid-ellagitannin metabolism (urolithin metabotypes), with potential consequences for human health.

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