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Review
. 2018 Sep:101:182-188.
doi: 10.1016/j.molimm.2018.05.030. Epub 2018 Jul 4.

The research progress of LncRNA involved in the regulation of inflammatory diseases

Kaili Liao  1 , Jiasheng Xu  2 , Weiming Yang  1 , Xiahong You  1 , Qionghui Zhong  1 , Xiaozhong Wang  3
Affiliations
Review

The research progress of LncRNA involved in the regulation of inflammatory diseases

Kaili Liao et al. Mol Immunol. 2018 Sep.

Abstract

Long non-coding RNA (lncRNA)is a non-coding RNA which lacks a complete open reading frame(ORF) and plays an important role in biological processes such as cell proliferation,differentiation and apoptosis. At present,the expression of lncRNA has been found to be abnormal in inflammatory reaction and inflammatory diseases. It might be involved in the development and progression of inflammatory diseases by regulating the expression of multiple genes and activation of signaling pathways. This article overviewed the progress in study on relationship between lncRNA and inflammatory diseases.

Keywords: Inflammation; Inflammatory bowel diseases; Inflammatory disease; Long non-coding RNA.

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