Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 2018 Aug;38(3):351-363.
doi: 10.1016/j.iac.2018.04.001. Epub 2018 May 17.

Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors

Almudena Matito  1 , José Manuel Azaña  2 , Antonio Torrelo  3 , Iván Alvarez-Twose  4
Affiliations
Review

Cutaneous Mastocytosis in Adults and Children: New Classification and Prognostic Factors

Almudena Matito et al. Immunol Allergy Clin North Am. 2018 Aug.

Abstract

The skin is one of the most frequent tissues affected in patients with mastocytosis, but cutaneous lesions are highly heterogeneous in shape, size, color, number, localization, and distribution. The World Health Organization recognizes 3 subtypes of cutaneous mastocytosis (CM): maculopapular CM (MPCM), diffuse CM, and mastocytoma of skin. An international task force of experts in mastocytosis has recently proposed subdividing MPCM into monomorphic and polymorphic, which could predict the duration of the disease in children. More research is warranted to develop an improved classification of CM that ideally should incorporate robust factors with prognostic impact on disease behavior.

Keywords: Classification; Cutaneous mastocytosis; Mast cell; Mastocytosis; Prognosis; Urticaria pigmentosa; WHO.

PubMed Disclaimer

Substances