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. 1985 Nov;17(6):449-52.
doi: 10.1111/j.2042-3306.1985.tb02553.x.

Sequences of papillomavirus DNA in equine sarcoids

K Trenfield, P B Spradbrow, B Vanselow

Sequences of papillomavirus DNA in equine sarcoids

K Trenfield et al. Equine Vet J. 1985 Nov.

Abstract

DNA was extracted from 14 equine sarcoids, electrophoresed and hybridised with a radioactively labelled probe of bovine papillomavirus type I (BPV 1) DNA under conditions of low stringency. Twelve sarcoids contained sequences of DNA that hybridised with the probe and that comigrated with BPV 2 DNA. The viral DNAs in four of these sarcoids differed from BPV 1 and BPV 2 DNA on restriction endonuclease analysis. One of four cell lines derived from sarcoids also contained BPV 1 related DNA. The results confirm the frequent presence in equine sarcoids of unintegrated papillomaviral DNA and suggest a role for papillomavirus infection in this disease.

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