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. 1985 Dec 15;41(12):1576-7.
doi: 10.1007/BF01964815.

TRH analogue with C-terminal thioamide group. Synthesis, receptor binding, TSH-releasing activity and alpha-MSH-releasing activity

M Kruszyński, G Kupryszewski, U Ragnarsson, M Alexandrova, V Strbak, M C Tonon, H Vaudry

TRH analogue with C-terminal thioamide group. Synthesis, receptor binding, TSH-releasing activity and alpha-MSH-releasing activity

M Kruszyński et al. Experientia. .

Abstract

A new TRH analogue containing a C-terminal thioamide group was synthesized. This peptide was shown to have receptor-binding affinity, and TSH- as well as alpha-MSH-releasing activities very similar to native TRH.

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References

    1. Chem Ber. 1970;103(3):788-98 - PubMed
    1. J Am Chem Soc. 1972 May 3;94(9):3102-6 - PubMed
    1. J Am Chem Soc. 1973 Aug 22;95(17):5677-9 - PubMed
    1. J Med Chem. 1981 Jun;24(6):692-8 - PubMed
    1. Mater Med Pol. 1980 Jan-Jun;12(1-2):129-35 - PubMed

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