Rates of membrane-associated reactions: reduction of dimensionality revisited
- PMID: 3001105
- PMCID: PMC2114064
- DOI: 10.1083/jcb.102.1.88
Rates of membrane-associated reactions: reduction of dimensionality revisited
Abstract
The hypothesis that reactions associated with intracellular membranes enjoy a kinetic advantage from a reduced dimensionality for diffusion is inconsistent with available data on lateral diffusion rates, membrane-substrate affinities, and endogenous concentrations of enzymes and their aqueous substrates.
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