Treatment of Prosthetic Joint Infection with Debridement, Antibiotics and Irrigation with Implant Retention - a Narrative Review
- PMID: 30013891
- PMCID: PMC6043472
- DOI: 10.7150/jbji.24285
Treatment of Prosthetic Joint Infection with Debridement, Antibiotics and Irrigation with Implant Retention - a Narrative Review
Abstract
Prosthetic joint infection usually requires combined medical and surgical therapy. While revision surgery is widely considered to be the gold standard surgical procedure, debridement, antibiotics and irrigation with implant retention is a very appealing alternative. There is however great controversy regarding its real worth with success rates ranging from 0% to over 90%. A number of different patient and host related variables as well as specific aspects of surgical and medical management have been described as relevant for the final outcome. Along this paper, the authors will provide the readers with a critical narrative review of the currently available literature while trying to provide concise and practical treatment recommendations regarding adequate patient selection criteria, proper surgical technique and optimal antibiotic therapy.
Keywords: Complications; Implant retention; Irrigation and Debridement; Prosthetic Joint Infection; Total Knee Arthroplasty, Total Hip Arthroplasty.
Conflict of interest statement
Competing Interests: The authors have declared that no competing interest exists.
References
-
- Grammatopoulos G, Bolduc ME, Atkins BL, Kendrick BJL, McLardy-Smith P, Murray DW, Functional outcome of debridement, antibiotics and implant retention in periprosthetic joint infection involving the hip: a case-control study. Bone Joint J; 2017. p. 99. -B(5): 614-22. - PubMed
-
- Gristina AG, Costerton JW. Bacterial adherence and the glycocalyx and their role in musculoskeletal infection. Orthop Clin North Am. 1984;15(3):517–35. - PubMed
Publication types
LinkOut - more resources
Full Text Sources
Other Literature Sources
